★ 6 SHiFT Codes as of September 2025
☆ Black Market Location
★ Elemental Weakness Chart
☆ Legendary Weapons
★ Builds: Vex | Amon | Rafa | Harlowe
☆ How to Respec Skill Tree

The Lifesteal Incarnate Bleed Vex build focuses on Kinetic Damage and Bleed for Vex in Borderlands 4. See the best builds, skills, weapons, guns, and gear to use for Vex, along with the best skill tree abilities and character playstyle.
| All Vex Guides | |
|---|---|
| Leveling Build | Vex Cosmetics | Boss Farm Build | Bleed Build |
| Vex Skill Trees and Voice Actor | |
List of Contents
| Jump to a Section! | |||||
|---|---|---|---|---|---|
| Skill Tree | Skill Progression | ||||
| Weapons | Ordnance | Shield | |||
| Class Mod | Enhancements | ||||
| Skill Tree | Vexcalation |
|---|---|
| Action Skill: Incarnate | |
The Vexcalation Skill Tree contains the Bloodletter skill, which allows Vex to deal a new Kinetic Status Effect to enemies that are hit by Critical Gun Damage.
This Build also focuses on multiple Kinetic Damage buffs from the skill tree, while using the Action Skill Incarnate to trigger various buffs which improve Vex' overall DPS.
| Jump to a Section! | ||
|---|---|---|
| Skill Tree | Skill Progression | |
| Passives | Capstone | |
| Skill Tree | Priority Skills | ||
|---|---|---|---|
The Fourth Seal |
From Levels 1~30, focus on unlocking the Heartpiercer Augment, specifically taking the skills that improve your Kinetic Damage, Gun Damage, and Lifesteal. Following our recommended skill path allows you to melt down bosses as early as Level 30.
Once you reach Level 31, focus on taking skills that improve Gun Damage, while also remembering to take Enchantment which gives you a +37.5% Kinetic Damage buff.
Cold Iron and Cursed Blade from the Fourth Seal tree provide minimal buffs, and can be re-invested instead in other Skills if you wish to increase Vex' Mobility or Action Skill cooldown rate instead.
Geistwave
|
||
| Tree | Vexcalation | |
|---|---|---|
| Effect | ||
| Instead of causing a Phase Explosion, Vex launches a Geistwave, dealing Ordnance Damage to enemies it passes through. Each affected enemy takes increased Damage for a Duration. | ||
Geistwave removes Incarnate's Phase Explosion, and instead replaces it with a forward facing Geistwave, which makes afflicted targets take +30% more damage received.
This allows Vex to simply pop her Action Skill while facing a Badass or Boss, and all the damage you deal towards the target will be increased by 30% for the next 15 seconds.
Heartpiercer
|
||
| Tree |
Vexcalation
(Branch 3) |
|
|---|---|---|
| Effect | ||
| Eldritch Blast now Sacrifices Health on use, but becomes a Piercing wave. Enemies hit take Damage, and Allies hit restore Health. Gain Bonus Damage and Healing based on Sacrificed Health. Eldritch Blast no longer has a Cooldown. | ||
For this build, Heartpiercer is the only Capstone you will unlock, but it offers no functional buffs for your intended gameplay.
You can still take this capstone and use Eldritch Blast when you need more healing, but it would be more ideal for this build to instead go for Critical Hits with Kinetic Weapons to quickly recover HP through your Lifesteal.
| Jump to a Section | ||
|---|---|---|
| Legendary Weapons | Best Manufacturer | Best Weapon Type |
| Legendary | Gun Overview |
|---|---|
Hot Slugger
|
Type: Shotgun Manufacturer: Jakobs Blazing Barrel: On kill, deal +30% Damage for 10s for a Maximum 3 Stacks |
| Borstel Ballista |
Type: Sniper Rifle Manufacturer: Jakobs [Alt-Fire] Shotgun: Fires a Shotgun that deals damage per shot |
These Legendary Jakobs Weapons have the best damage potential when using this build.
Both the Hot Slugger and the Borstel Ballista have high single shot damage, with the only condition you need to satisfy is to aim for weak spots to guarantee a crit.
Jakobs weapons are known for their high Kinetic damage, which makes it perfect for this build.
Jakobs weapons also have augments and modifiers for Critical Hits, allowing it to synergize well with this build, regardless of what gun parts you have on your Jakobs weapons.
Since this build relies on Bleed and Kinetic Damage, you can use any Kinetic Gun and it will synergize well with this build.
As much as possible, avoid elemental weapons, as these will not synergize well with your Skill loadout.
| Ordnance | Type and Overview |
|---|---|
| Vampiric Vivisecting Throwing Knife |
Grenade Ordnance Penetrator Augment: Damage to the impacted target are automatic Critical Hits for 5s |
The Vampiric Vivisecting Throwing Knife which comes with the Penetrator Augment enables this build exceptionally well, due to its guaranteed critical hits for 5 seconds.
Currently, the guaranteed critical hit from Penetrator allows bleed to Critically Hit, resulting in insane amounts of damage after it procs.
| Shield | Type and Overview |
|---|---|
| Firewerks |
Armor Shield Bundled: On kill, spawns Missiles that home in on nearby enemies and deal damage each Kinetic Element Recommended |
Firewerks is the best offensive shield option for the Bleed Vex Build, due to its Bundled augment, which spawns missiles upon killing an enemy.
When used alongside Jakobs weaponry, you can randomly get kills when dealing critical hits, since Jakobs weapons usually have the augment that ricochets critical hits, which will then enable your Missiles, resulting in additional DPS.
Teen Witch amplifies the Lifesteal Buffs you gain from Blood is Power, and Gun Damage from Conjunction.
This also massively boosts Vex' survivability, granting you Overshield when you deal damage while both your HP and Shield are full.
| Enhancement | Effects |
|---|---|
| Jakobs |
・Bounce Pass - Guns with Jakobs-licensed parts increase the number of possible Ricochets by 1. ・Sequencer - Guns with Jakobs-licensed parts grant consecutive Critical Hits a stacking +5% Bonus Damage, for a Maximum of 8 Stacks. |
Equipping a Jakobs enhancement with either Bounce Pass or Sequencer greatly improves your DPS when using this build.
Bounce Pass allows your Critical Hits to bounce to more targets, further enabling Firewerks missiles, while Sequencer increases your overall damage, allowing you to deal more damage with your gun and bleed.
Vex' Incarnate Bleed build specializes in Kinetic Bleed damage, using Jakobs Weapons to trigger the effect.
This Build also features multiple Lifesteal and Healing effects, which both amplify Vex' damage, and improve her survivability.
Due to the extremely high damage this build can output, this build is viable for all end-game content, including Ultimate Vault Hunter Mode.
Even without the Vampiric Vivisecting Throwing Knife, this build will still be viable due to its high DPS and Survivability, but the rate at which it can clear bosses will be significantly slower.
What is Ultimate Vault Hunter?
Since this build relies on Vex' Bleed mechanic, it is extremely important to land critical hits as much as possible.
With the Vampiric Vivisecting Throwing Knife, your Bleed will also Critically hit, allowing for rapidly stacking damage to even bosses, like shown in the clip above.

Best Builds for Each Vault Hunter
| Character | Build |
|---|---|
Vex |
|
Rafa |
|
Amon |
|
Harlowe |
Lifesteal Incarnate Bleed Vex Build

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